Okkert I. Pharmacognostic study of the Rhaponticum carthamoides Willd. and reception of the substances-standarts

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0402U003821

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

22-11-2002

Specialized Academic Board

Д64.605.01

Essay

The study is devoted of the pharmacognosy's of assessment Rhaponticum carthamoides Willd. The presence of various groups of biologically active substances, such as flavonoids, ecdysones, oxycinnamic acids, amino acids, carbohydrates, glucofructants has been investigated. The method of the quantitative definition of the summary of the fructozans after their acid's transformation has been developed. For the first time fixed amino acids and microelements of the Rhaponticum carthamoides Willd.. The way of reception of the substances - standards, such as the lutheolin-standard and ekdizon-standard has been developed. The structure of the 30 substances fixed: 17 flavonoids (12 aglicons and 5 glycosides), 5 cumarines, 6 oxycinnamic acids, 2 ecdysones. For the first time we carried out comparative morphology-anatomic analysis of the underground's parts wildgrowing Rhaponticum carthamoides Willd. with cultivated samples. The Projects of Pharmacopoeia monographies "Root of the Rhaponticum carthamoides L.", "Lutheolin-standard", "Ekdisteron-standard" have been developed.

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