Yakovleva T. The condition of fetoplacental complex at the bacterial polyhydramnion

Object of research: bacterial polyhydramnion. The purpose of research: to study metabolic and hystohimical processes in amnion-cytothrophoblast-decidual tissues at bacterial polyhydramnion and to increase efficiency of its treatment on the basis of antibacterial therapy by cephalosporine II generations system enzymotherapy. Methods of research and the equipment: Carried out research of hormonal fetoplacental function; bacteriological research of urogenitale tract in the pregnant woman, hydramnion, amnion, newborns; the biophysical structure of a hydramnion was studied; cardiotocograms of the fetus; it was carried out ultrasonic fetometry, placentometry, studying of hydramnion volume; pathomorphology research of amnion; clinical laboratory investigation of newborns. Theoretical and practical results: It is developed and introduced into practice etio-patogenety method of bacterial polyhydramnion therapy by cephalosporine and system enzymotherapy, that allows to prevent intra-uterine infection of the fetus, assists a birth of viable children. Novelty: risk factors of occurrence of bacterial polyhydramnion, basic activators of infectious process in amnion-cytothrophoblast-decidual tissues were established, way of invasion is specified, spectrum of their sensitivity to antibacterial preparations is determined. Are determined histologic and immunomorphology an attribute of defeat of amniom tissues at bacterial polyhydramnion. Efficiency and the expediency of cephalosporine and system enzymotherapy complex application at bacterial polyhydramnion are proved. Degree of introduction: results are entered into work of maternity hospitals №2, 4, 5 of Kharkov. Sphere of application: medicine, obstetrics.