Martiushova V. Physical-chemical properties of polyvinylpyrrolidone and scientific substantiation of their effect on the quality of medicines

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0403U002151

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

12-06-2003

Specialized Academic Board

Д 26.613.04

Essay

The dissertation is dedicated to the evaluation of the physical-chemical properties of different molecular weights (M.w.) polyvinylpyrrolidone (PVP) influence on biopharmaceutical characteristics of the sparingly soluble in water drug substances: paracetamol - in aqueous solution and atenolol - in solid dosage form; investigation of the nature of PVP macromolecules interaction in water and electrolytes solution; the development of the quality control methods for PVP substances with M.w. 8000, M.w. 12600 and medicine «Neohemodez».

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