Chepel Р. Synthesis, transformation and biological activity in the family of derivatives of 1,2,4-triazole

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0403U002408

Thesis Registration Form

0403U002408.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

12-06-2003

Specialized Academic Board

Д 26.613.04

Essay

Worked out preparative synthetic procedures of some 5-alkylthio-, 5- carboxyalkylthio-, 5-alkoxycarbonylthio-, 5- heterylthio-3-(3-R-1,2,4-triazolyl-5-thiomethyl)- 1,2,4-triazols and derivatives of 1,2,4- triazolo(3,2-b)- and 1,2,4-triazolo(3,4-b)thiazole. Hydrazides, ilidenhydrazides and salts are synthesized for 3-(3-R-1,2,4-triazolyl-5-thiomethyl)- 1,2,4-triazolyl-5-mercaptacarboxylic acids. Structure of synthesized compounds is confirmed by methods of UV-, IR- spectroscopy, PMR- and mass-spectrometry, and their identity - by thin-layer chromatography.

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Files

Автореферат-ЧПВ-А4.doc

Синтез.doc

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