Buryan A. The chemical and toxicological investigation of Fluoxetine

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0403U003551

Thesis Registration Form

0403U003551.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

10-10-2003

Specialized Academic Board

Д64.605.01

Essay

The thesis is devoted to chemical and toxicological analysis of antidepressive medicine - Fluoxetine. The methods for the identification of Fluoxetine have been offered, the conditions of Fluoxetine determination by the TLC and HPLC methods with some other medicines have been offered. The UV-spectrophotometric, extraction-photometric and HPLC-method of quantitative determination of Flouxetine have been worked out. The conditions of Fluoxetine extraction from aqueous solutions by organic solvents in dependence on pH medium have been studied. The comparative study of generally accepted extractive methods in chemical and toxicological analysis of substances for Fluoxetine has been conducted. The effective extractive methods of Fluoxetine from biological objects and biological liquids have been offered. On the basis of the carried out investigations the scheme of Fluoxetine chemical and toxicological analysis in extracts from biological material has been offered

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Files

AREF.DOC

DissertFluoxetine--Література.doc

DissertFluoxetine--Розділ 1.doc

DissertFluoxetine--Розділ 2.doc

DissertFluoxetine--Розділ 3.doc

DissertFluoxetine--Розділ 4.doc

DissertFluoxetine--Розділ 4.doc

DissertFluoxetine--Розділ 5.doc

DissertFluoxetine--ТИТУЛ.doc

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