Sheludko Y. Obtaining and phytochemical analysis of Rauvolfia serpentina hairy root cultures as a source of new indole alkaloids

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U001353

Thesis Registration Form

0404U001353.pdf

Applicant for

Sheludko Yuriy Vsevolodovich

Specialization

03.00.20 - Біотехнологія

Date of defense

18-03-2004

Specialized Academic Board

Д 26.202.01

Essay

The thesis is focused on the investigation of the indole alkaloid patterns in Rauvolfia serpentina Benth. ex Kurz hairy roots. 16 known alkaloids were found in the hairy root culture of R. serpentina, 9 of them were detected in the R. serpentina hairy roots for the first time. Four new alkaloids were also isolated, belonged to raumacline and sarpagine group. The biosynthetic pathways of the new indole alkaloids were suggested. Treatment with methyl jasmonate caused 2-8 fold increase of indole alkaloid contents.

Thesis supervisor

Gleba Yuriy Yurievich

Official opponents

Кунах Віктор Анатолійович
Сарнацька Вереса Василівна

Files

Sheludko_diss.doc

aref.doc

Similar theses

0424U000017

Olena Stotska

Biotransformation of brewery waste to obtain biogas and fodder biomass

0523U100161

Iryna B. Rusyn

Biotechnological fundamentals of electricity generation in plant-microbial biosystems

0423U100003

Pokhylko Yurii Mykolaiovych

Biological properties of bacteria of the genus Lactobacillus isolated from the digestive tract of rabbits, promising for the creation of probiotic preparations.

0422U100046

Irodov Dmitry M.

Study of the mesenchymal stem cells therapeutic potential in the conditions of multiorgan dysfunction syndrome against the background of long-term toxic damage to the body

0422U100049

Lialyk Anastasiia Tarasivna

Biotechnological aspects of cheese making with high content of Оmega-3 fatty acids