Pokhylko Y. Biological properties of bacteria of the genus Lactobacillus isolated from the digestive tract of rabbits, promising for the creation of probiotic preparations.

The dissertation presents the results of studies aimed at screening bacteria of the genus Lactobacillus, promising the creation of probiotic preparations for rabbits. It is known that during the weaning period there is significant mortality of young rabbits, often caused by opportunistic infections. Based on the limitation of the use of antibiotics in animal husbandry to solve this problem, there has been a growing interest in drugs based on live microbial cultures - probiotics - that show a pronounced preventive effect against infectious diseases of the gastrointestinal tract. However, probiotics used today in rabbit breeding are universal and recommended for various types of animals. To ensure the maximum effectiveness of a probiotic preparation, it should be based on representatives of the obligate microbiota of the gastrointestinal tract of the animal species for which it is used. Therefore, screening of biologically active representatives of the obligate microbiota of the gastrointestinal tract of rabbits remains an urgent task. Studies have established that, regardless of the type of feeding, lactic acid bacteria are the dominant group among the main representatives of the microbiota of the gastrointestinal tract of rabbits. Taking into account the large number of studies demonstrating the effectiveness of probiotic preparations based on bacteria of the genus Lactobacillus, the selection was aimed at isolating active strains of this genus. There were isolated and investigated 250 isolates, which were attributed to bacteria of the genus Lactobacillus by physiological-biochemical and morphological-cultural characteristics.