Susak I. Hemocoagulation homeostasis condition and opportunities of correction of their changes in patients with primary pulmonary hypertension and congenital heart diseases on stage of Eisenmenger syndrom at long supervision.

In thesis the data describing a condition of curtailing blood system and functional activity of blood platelets and erythrocytes at primary pulmonary hypertension and congenital heart diseases on stage of Eisenmenger syndrom are submitted. Is established, that the changes of coagulation potential, adequate to different stages of disseminated intravascular coagulation, and in most cases - by its third, hypocoagulation, phase are characteristic for these diseases. The informativity of hemostatic parameters is appreciated concerning the 1-year's forecast survival rate of patients with primary pulmonary hypertension. The one-orientation of changes plasmatic, blood platelets and erythrocetic section of the system of hemostasis is established at both forms vascular pulmonary hypertension. The changes of arterio-venous difference of parameters of blood coagulation activity at the patients with primary pulmonary hypertension and Eisenmenger syndrom in comparison with the donors and among themselves are analysed. The results of 1-year's supervision behind dynamics of parameters thrombocytic and plasma hemostasis of the patients under influence of treatment with use of therapy by aspirin are submitted. The influence erythrocytpheresis on parameters coagulation blood of activity at patients with secondary polycythemia is investigated.