Мoeen F. Pharmacognostic study of Lathyrus cіcera L. and Lathyrus vernus L. herb

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U001445

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

09-04-2004

Specialized Academic Board

Д64.605.01

Essay

As a result of the gualitative reactions and chromatographic analysis the presence of flavonoids, isoflavonoids, oxycinnamic acids, tannins, amino acids and fatty acids has been proven in Lathyrus cicera and Lathyrus vernus herb. The qualitative composition and the quantitative content of amino acids, fatty acids and mineral elements have been determined. A accumulation dynamics for biologically active substances in Lathyrus species investigated have been studied. For the first time 9 compounds: 6 flavonoids and 3 phenolcarboxylic acids - have been isolated from Lathyrus cicera herb and 11 compounds - 7 flavonoids, 2 coumarins and 2 phenolcarboxylic acids - have been isolated from Lathyrus vernus herb. For the first time the method for obtaining of dry extracts from Lathyrus cicera and Lathyrus vernus herb has been developed and their pharmacological activity has been studied. For the first time anatomic structure of Lathyrus cicera and Lathyrus vernus herb has been studied, the main diagnostic features of the raw material have been established. The projects of analytical normative documentation for the raw material "Lathyrus cicera herb" and "Lathyrus vernus herb" have been elaborated

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