El I. Synthesis and biological activity of new amino-acids derivatives of 1,4-naphtoquinone.

Object - Nucleophil substitution reactions for synthesis of amino-acids 1,4-naphtoquinone(s derivatives, complexe formations of them with metal cations; mean - synthesis a new 2,3-disubstutes-1,4-naphtoquinones with amino-acid fragments, studies a complexe formation with metal cations and search of potentials drugs of them; methods - organic synthesis, spectrals methods (IR-, PMR-, MB-, UV-spectroscopis), elementaire analysis, chromatography, biological and physiological screning, mathematical statistics; novelty - syntesised a new aminoacids derivatives of 1,4-naphtoquinone, their potasium(s and sodium[Р1](s salts, naphtoquinone(s carnosine substitutes cuprum and zincs helates in their basis, founded compounds with high activity; results - used in education processus in National University "Lvivska polythechnica", Lviv National university after name I.Franko, Institute of animal(s biology UAAS and in company "Halychpharm", area - pharmacie.