Zaloilo I. Dynamics of nonlinear processes of sceletal muscle fiber contraction

The thesis presents the results of investigation of the dynamics of contraction of singles m.tibialis muscle fibers as a response to the frequency-modulated stimulating signal. It is determined that before the fiber passes into the state of tetanic tension the phenomenon of the generation of additional muscle force takes place. This phenomenon is detected to depend on stimulation characteristics. Frequency and amplitude boundaries of this phenomenon are determined. Nature of the growth of the stimulated force of fiber contraction is shown to depend on the nature of a preceding condition. Timing characteristics of changes of the contraction force are determined to also depend on the direction of the trajectory of the stimulating signal. Mathematical model of the "speed and strength of fiber isotonic contraction" relationship is developed and put to the test. This model is proved to adequately describe the experimental data.