Terletska O. The role of photoperiod changes as an environmental factor in the disturbance of kidney functions

The thesis is dedicated to the study of the influence of photoperiodic on excretory, ionic-regulative and acid-regulative functions of the kidneys. In experiments on pubertal white laboratory male rats which have been keeping in different light regimes the influence of the photoperiod duration on the circadian rhythm of the mentioned above functions of the kidneys and special features of architectonics, reconstruction of kidneys biorhythms was experimentally grounded. Photoperiodic disturbances of proximal and distal natrium-ions transportation, chronorhythms changes of natrium and potassium ions excretion, disturbance of natrium-potassium homeostasis were distinguished. A more expressed influence of constant lighting on the most of these indeces, if compared with constant darkness, was proved. The dependence of acid-regulation function of the kidneys upon photoperiod conditions was established. It was found that the changes of photoperiod not only disturb average daily indeces of excretory, ionic-regulative and acid-regulative functions of the kidneys, but cause extraordinary reconstruction of chronorhythms structure.