Andrey N. The prognostic, diagnostic and treating aspects of hyperplastic processes of endometrum

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U004937

Applicant for

Specialization

  • 14.01.01 - Акушерство та гінекологія

21-12-2004

Specialized Academic Board

Д 05.600.01

Vinnytsia National Pirogov Memorial Medical University

Essay

Object - complex studying of factors which participate in regulation of a functional condition endometrum; methods clinical, tool, laboratory, mathematic-statistical; novelty - it is proved, that to the basic ethiopathogenetic the mechanism of occurrence of polyps endometrum fibrous and glandula-fibrosis structures is center prolipheration of stroma on a background chronic persistant infections; for the first time it is proved, that hyperplastic processes endometrum are not only result raised cellular prolipheration, but also consequence of resistency of cells endometrum to processes apoptosis; are specified and added dopplerometrical parameters of vessels endometrum at his hyperplastic processes, are analysed and revealed pathognomical difference-diagnostic criteria of separate kinds of the given pathology; For the first time it is scientifically proved and approved local application of gestagen and levonorgestrel for treatment HPE as intrauterine levonorgestrel-releasing system; results - forecasting, improvement of methods of inspection, the system of conducting and a pathogenetic substantiation of treatment of patients with hyperplastic processes endometrum is differentiated; branch - medicine

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