Ruslan N. Forecasting of passage of a acuite cholecystitis and itscomplications

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U004984

Applicant for

Specialization

  • 14.01.03 - Хірургія

21-12-2004

Specialized Academic Board

Д 05.600.01

Vinnytsia National Pirogov Memorial Medical University

Essay

Object - sharp inflammatory process of a bilious bubble; methods - clinical, tool, biochemical, renthenological, endoscopical, morphological, statistical; novelty - on the basis of complex researches is shown, that AC is accompanied by formation a inflammation-metabolic syndrome; is determined, that in blood from the center of pathological process a lot cytocine, homocysteine, hypoxanthine and xanthine collects considerably, than in a blood circulatory system, the scales of these changes are greatest at gangrenely to the form AC and least - at catarality to its form; for the first time is appreciated diagnostic and prognosis the importance of levels of interleukin-6, of the tumor necrosis factor-alpha, homocysteine, parameters cytopathic hypoxia, oxidative and nitrosative stress, parameters of a mineral exchange as the tests for differentiation of the not complicated and complicated forms AC and predictions of occurrence postoperative is pyoinflammatory of its complications; results - are developed theapproaches to forecasting and differentiation pyoinflammatory of complications by research of levels cytokines, homocysteine, parameters cytopathic hypoxia, oxidative and nitrosative stress, level calcium and magnesium, phosphorus on up- to and postoperative stages of treatment AC; branch - medicine

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