Tsyts A. Нealing of surgical wounds of kidneys and a bladder in conditions of application multicomponent biological wound coverings (experimental research).

The dissertation is devoted to a problem of application new haemostatic and adhesive preparations in urology. It is first set that multicomponent biological haemostatic adhesiv wound coverage of ТК carries out on the process of cicatrization of surgical wounds of kidney and urinary bladder multifactor action, basis of which is made by absence of the expressed inflammatory cellular infiltration that provides forming of optimum connecting-tissue scar at reduction of terms of exudation and motion of reparative processes. For the first time obtained adhesive property of ТК in relation to the different layers of wall of urinary bladder, namely: impossibility of adhesive to the mucus shell and, opposite, reliability of fixing to submucosis, muscular and serouse layers. For the first time were determined terms of degradation of ТК on the internal (2 weeks) and external (6 weeks) surfaces of urinary bladder and, thus, the fact of speed-up destruction of the noted wound coverage is set in the conditionsof contact with urine. Confirmed nephrones - saved role of application of ТК for closing of surgical wounds of kidney cortex. It is first obtained that ТК at closing of surgical wound of kidney allows to prevent distribution of reactive inflammatory reaction on intactiv cortex and pelvis, and also development hydronephrosis transformations which take place after suturing of cortex. It is first obtained that the use of ТК at the resection of kidney provides renewal of its true shape due to forming of adequate connective tissue scar. Experimental data of application of ТК gives the evidence-based results providing for the wide use of progressive surgical technology in practice of clinical urology.