Object of investigation: germanium(IV) coordination compounds with diethylenetriaminepentaacetic, ethylenediaminetetraacetic and oxyethylidenediphosphonic acids and different-metal complexes on the basis of them with some s-, d-, and f-metals ions. Aim of investigation: to synthesize new uniform- and different-metal germanium(IV) complexonates, to reveal their coordination-chemical, structural peculiarities and functional properties. Methods of investigation: elementary and X-ray phase analysis, conductivity and magnetic susceptibility measurements, thermogravimetry, spectral (diffuse reflection, electron spin resonance and IR spectroscopy), X-ray crystal structure analysis. Theoretical and practical results: the methods have been devised and 31 novel uniform- and different-metal germanium(IV) complexonates on the basis of diethylenetriaminepentaacetic, ethylenediaminetetraacetic and 1-oxyethylidenediphosphonic acids have been synthesized in aqueous solutions. It has been stated the germanium coordination polyhedron to be distorted octahedron with complex-forming cation GeOH3+ in all uniform-metal complexes. Germanium forms mononuclear complexes with polyaminocarboxylic complexones, and hexanuclear one with ligand bridge function with phosphonic complexone. A number of complexes with s- (Li, Na, K, Mg, Ca, Ba), d- (Co, Ni, Cu, Zn) and f- (Pr, Nd, Gd, Tb) metals has been obtained when diethylenetriaminepentaacetato-, ethylenediaminetetraacetato- and oxyethylidenediphosphonatohydroxy-germanium acids with vacant donor centres were used as construction blocks. It has been shown all different-metal complexonates were built by supramolecular type architecture realized by different types of intermolecular H-bonds.Their composition and structure are determined by nature of the second metal s-, d- or f- (salts, cation-anionic or heteronuclear) with conservation of initial germanium anione structure. It has been shown the high ability of a number of germanium complexes synthesized to biological activity (antioxidant, cardiotropic, hepatoprotecting, anti-caries) to be determined by synergism of pharmacological action of germanium, ligands and other metals, and its variety to be connected with the fact that complexes studied to be interferone inductors and perspective immune-pharmacological remedies of regulation of disbalance of immune system. Degree of inculcation: the developed methods have been introduced into the practice of work of department general chemistry and polymers (the individual part of special course devoted to complex formation and physical-chemical investigation of coordination compounds. Field of application: coordination chemistry.
