Borodayev I. The Miniinvazivnie methods of medical treatment of sharp destructive pancreatita in the conditions of correction of the immunomoduliruyushey system by interferon

Subject of the study: . Destructive forms of acute pancreatitis Purpose of the study: To improve the efficacy of surgical treatment of destructive forms of acute pancreatitis using minimum invasive techniques in combination with immune-modulating therapy with interferon. Methods of research: General clinical, laboratory, biochemical, immunological, instrumental, bacteriological, statistical. Practical significance of the obtained results: Reasonability of minimal invasive surgery and interferon administration in patients with destructive acute pancreatitis was substantiated. Scientific novelty: Improvement of cellular and humoral immunity parameters under the influence of immune-modulating therapy in the complex of therapeutic measures in the post-surgical period was shown. Effective correction of caused by acute destructive pancreatitis thiole-disulfide system dysbalance as a result of minimum invasive surgery and immune-modulating therapy was established. Preventive significance of minimum invasive surgery as to purulent complications in patients with acute destructive pancreatitis in the conditions of interferon system correction was shown. Degree of introduction: The developed methods of treatment were introduced into clinical practice of city hospitals No. 11, 12, 2 (Odessa), Ilichevsk hospital. Sphere of application: medicine, surgery.