Kolker I. Neuropathophysiological mechanisms of optic and auditory disorders in children with spastic forms of cerebral palsy

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U001092

Thesis Registration Form

0405U001092.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

16-03-2005

Specialized Academic Board

Д 41.600.01

Odessa National Medical University

Essay

The Dissertation is Dedicated to the rationale of neuropathophysiological mechanisms of visual, auditory and cognitive disorders in children having spastic forms of cerebral palsy (CP), basing upon the evoked potential studies and upon the blood level of proinflammatory cytokines TNF-? and IL-1?. It has been shown that there exist pathological changes in electrogenesis of the optical (84,1 %) and auditory (63,5%) sensory system, as well as changes of compensatory adaptational character (44,3%) in children with spastic CP. It has been proved for the first time that the overproduction of cytokines TNF-? and IL-1? plays its pathogenetic role in the development of pathological changes in the central parts of sensory systems and enhancement in cognitive deficit in children with CP at the residual stage

Read more

Files

aref.doc

dis.doc

Similar theses

0524U000146

Hennadii F. Stepanov

Pathophysiological mechanisms of ionizing irradiation influence on muscle tissue metabolism

0524U000051

Vitalii Kyryk

Pathogenetic mechanisms of realizing the regenerative potential of somatic stem cells, taking into account the criteria of their quality and efficiency

0523U100270

Olha H. Kmet

Pathogenic substantiation of the effectiveness of modulators of GABA-ergic and renin-angiotensin systems in experimental neurodegeneration

0523U100201

Iryna I. Kamyshna

Molecular mechanisms in the development of psychoneurological complications in patients with thyroid diseases: predicting onset and search for pathogenetic therapy

0423U100032

Havalko Anna Vasilivna

The role of hypoxia in impaired glucose tolerance in the elderly and ways of correction