Levkovets I. Development of instrumental analytical biotests and studying their basic characteristics for the determination of environmental toxicity of substances

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U001345

Thesis Registration Form

0405U001345.pdf

Applicant for

Specialization

  • 03.00.20 - Біотехнологія

04-04-2005

Specialized Academic Board

Д 26.240.01

Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine

Essay

The object of investigation - biotests for environmental toxicity and optical immunosensor for toxicants. The aim - development of express biotests based on chemiluminescence of exometabolites by Daphnia magna and based on bacterial bioluminescence using Vibrio fisheri, development of an Optical Waveguide Lightmode Spectroscopy (OWLS) immunosensor for individual toxicants. Methods: luminometric, laser-spectroscopy, immobilization of macromolecules on chip surface. Effects of given toxicants on chemi-/bioluminescence, the effect of immunosensor format on analytical sensitivity. Results can be used in environmental analysis, quality control of water purification. Field of application: scientific and industrial (biosensor production).

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Files

Dis.doc

aref.doc

aref_nazva.doc

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