Stepanov G. Mechanisms of the disturbance of creatine metabolism in the posterity of the irradiated rats

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U002826

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

22-06-2005

Specialized Academic Board

41.600.01

Essay

Firstly on the base of own investigation disturbance of the creatine kinase system activity in the organisms of the irradiated rats' posterity takes place because of the decreasing of the amino acids-precursors of the creatine' content in the tissues and activation of their excretion with urine, decreasing of the guanidine acetate' methylation, disturbance of the isoenzymatic spectrum of the creatine phosphokinase - that is one of the reasons of the adenile nucleotides pull' decreasing in the muscles was show

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