Kachmarska M. NO-dependent processes in liver and their connection with monocytar-endothelial associations in chronic hyperimmunocomplexemia

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U003598

Thesis Registration Form

0405U003598.pdf

Applicant for

Kachmarska Marta Olegivna

Specialization

14.03.04 - Патологічна фізіологія

Date of defense

30-09-2005

Specialized Academic Board

Д 58.601.01

I. Horbachevsky Ternopil State Medical University

Essay

The indexes of Nitrogen oxide system and cyclic nucleotides in liver, monocytes and endotheliocytes – in chronic hyperimmunocomple-xemia, the ultrastructural changes and its correction by quercitine were studied According to the received data – in chronic hyperimmunocomplex process observed was a considerable increase of iNOS activity and decrease of cNOS activity, the lowering of NO2? and NO3? sum, and of cAMP and cGMP levels in all investigated test-objects, destructive changes in tissues of liver, monocytes and endoteliocytes. Corvitine normalizes NO system, levels of cyclic nucleotides. Corvitine injection were accompanied by positive changes of ultrastructure of liver, monocytes and endotheliocytes.

Thesis supervisor

Bidjuk M.M.

Official opponents

Гоженко А.І.
Коляда Т.І.

Files

aref.doc

Качмарська М.О. Дисертація-1.Tutylna,zmist,skorochennja.doc

Качмарська М.О. Дисертація-2. Vstup.doc

Качмарська М.О. Дисертація-Rozdil 1.doc

Качмарська М.О. Дисертація-Rozdil 2.doc

Качмарська М.О. Дисертація-Rozdil 3.doc

Качмарська М.О. Дисертація-Rozdil 4.doc

Качмарська М.О. Дисертація-Rozdil 5.doc

Качмарська М.О. Дисертація-Rozdil 6.doc

Качмарська М.О. Дисертація-Rozdil 7.doc

Качмарська М.О. Дисертація-Spusok literatyru.doc

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