Moskalyuk A. Electrical activity and postsynaptic currents in neurons in rat hippocampal culture

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0405U004908

Thesis Registration Form

0405U004908.pdf

Applicant for

Specialization

  • 03.00.02 - Біофізика

06-12-2005

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

It was shown that GABAergic neurons in hippocampal culture are divided in two groups by their firing characteristics. It was demonstrate that the presynaptic neuron exerts a determining influence on the nature of the postsynaptic current. The electrophysiological properties of excitatory neurons and regular spiking inhibitory interneurons could be reliably distinguished and correlated with their morphology and expression of K+ channels subunits. We conclude that, possibly, the mechanisms of electrical excitability responsible for neuron's regular spiking electrical activity differ between inhibitory and excitatory interneurons.

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Files

avtoreferat.doc

disser_Moskalyuk.doc

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