Prokopchuk Y. Clinical and pathogenetic substantiation of using ozone therapy in complex rehabilitation treatment of patients with ulcerous disease of the duodenum

The dissertation covers the clinical and pathogenetic substantiation of using ozone therapy in complex rehabilitation treatment of patients with ulcerous disease of the duodenum with the purpose of increasing efficacy of therapy and prevention of recurrences of ulcer formation.There was studied efficacy and established peculiarities of different techniques of ozone therapy (internal intake of ozonized water, small autohemotherapy of ozone oxygen mixture) at the rehabilitation stage in 120 patients with ulcerous disease of the duodenum on the basis of results of complex clinical, laboratory and instrumental examinations.It is proved that application of ozone therapy increases significantly the efficacy of rehabilitation treatment causing regress of pain, dyspeptic and asthenovegetative syndromes, palpation tenderness, enhancing healing of the ulcerous defect, increasing eradication of helicobacter pilori, prolonging the period of clinical remission and reducing the posteradication manifestations. The therapeutic effect of medicinal complexes with the use of ozone therapy is based on activation of trophic mechanisms and enhancing of reparative processes in the mucous membrane of the gastroduodenal area.