Kaplaushenko A. Synthesis, physical-chemical and biological investyigations of S–derivatives 5-(2,-3,-4- nitrophenyl)–1,2,4–triazole–3–thions

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U001688

Thesis Registration Form

0406U001688.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

30-03-2006

Specialized Academic Board

Д 26.613.04

Essay

The main aim of the dessertation is the synthesis of new high –performance and low – toxic compounds whith potential antimicrobial,diuretic, analeptic antiinflammmatory, antiischemic, and antioedem (asto the brain oedem wich is conditioning of widestrips vibration)activities among the 5-(2,-3,-4- nitrophenyl)–1,2,4 – triazole–3–thions and their S–derivatives, estab lishing of regularity of ties between chemical structure, biological effect and application, recommending of new effective drugs for before clinical actions. Morfolining salt 2-(5-(4-nitrophenyl)-l,2,4–triazol-3-ilthio)-acetas acid, which has express antioedem effect as to the brain oedem which is conditioning of widestrips vibration. We worked out the method of laboratory receiving, technical condition

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АвторефКапл1Титул.doc

АвторефКапл2.doc

Д Каплаушенко.doc

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