Kulagina M. Pharmacognosical study of рlants of Duschekia Opiz genus.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U001930

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

21-04-2006

Specialized Academic Board

Д64.605.01

Essay

A comprehensive pharmacognosical study of the bark, leaves and infructescences of D. viridis, D. maximowiczii and D. fruticosa is carried out. 19 individual compounds (3 derivatives of benzoic acids, 5 oxycinnamine acids, 3 coumarins, 4 flavonoids and 4 alagotanids) are isolated and their structure is determined. The aminoacid, fatty acid and microelement compositions of the рlant raw material a determined. A comparative morphological and anatomical study and the quantitative determination of biologically active substances of the species of Duschekia genus are made. The pre-clinical pharmacological study of biological complexes extracted from the vegetative and generative organs of D. viridis is carried out. A method for obtaining of the special sum of polyphenol compounds with the antimicrobic, anti-inflammatory and diuretic actions (called by "Duschekin") from the mature infructescences of D. viridis is invented

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