Kalishchuk O. Endoscopic treatment of vesicoureteral reflux in children with neurogenic dysfunction of the urinary bladder

The dissertation has been proved that neurogenic dysfunction of the urinary bladder in patient with vesicoureteral reflux (VUR) increasing frequent aggravations of pyelonephritis, complicated clinical course and accelerated deep of anatomyfunctional renal changes in compare to patient with VUR without breach function of the urinary bladder. The author arguments patogenetic substantiation of mentioned complications: available of the constantly intermit intraluminary hypertension in kidneys in phase fill ("quient") of the urinary bladder. The author developed the new method of subureteric implantation of biologic neutral substance. The author developed absolute and relative evidence to the endovesical treatment of VUR. The proposed pathogenetic direction of treatment of VUR in children with neurogenic dysfunction of the urinary bladder that to basis on the maked endoscopic antireflux mechanism and long-term making pharmacologic and physiotherapeutic measures that to maked normal functional of the urinarybladder.