Prysyazhna O. Infringement of NO-dependent regulation of contractive reactions of heart and vessels at experimental diabetes mellitus

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U002896

Thesis Registration Form

0406U002896.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

20-06-2006

Specialized Academic Board

Д26.198.01

Essay

We have revealed a complex of disturbances of endothelium-dependent reactions at streptozotocininduced diabetes. At an animal with experimental diabetes mellitus the growth of stiffness and oxygen cost of the work of vascular smooth muscles and myocardium was shown. Is shown, that possible mechanisms of development of such disorders are a depression of NO synthesis, hyperglycaemia and development of oxidative stress. Under melatonin and L-arginin action the partial restoration of the broken reactions is observed.

Read more

Files

автореферат Присяжна О.Д.doc

дисертація Присяжна О.Д..doc

Similar theses

0524U000146

Hennadii F. Stepanov

Pathophysiological mechanisms of ionizing irradiation influence on muscle tissue metabolism

0524U000051

Vitalii Kyryk

Pathogenetic mechanisms of realizing the regenerative potential of somatic stem cells, taking into account the criteria of their quality and efficiency

0523U100270

Olha H. Kmet

Pathogenic substantiation of the effectiveness of modulators of GABA-ergic and renin-angiotensin systems in experimental neurodegeneration

0523U100201

Iryna I. Kamyshna

Molecular mechanisms in the development of psychoneurological complications in patients with thyroid diseases: predicting onset and search for pathogenetic therapy

0423U100032

Havalko Anna Vasilivna

The role of hypoxia in impaired glucose tolerance in the elderly and ways of correction