Starzhinska O. The clinical and diagnostic value of B-natriuretic peptide plasma concentration and the polymorphism of angiotensin II receptors genes in patients with essential hypertension

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U003354

Applicant for

Specialization

  • 14.01.11 - Кардіологія

27-06-2006

Specialized Academic Board

Д 26.616.01

State Institution National Scientific Center "The M.D. Strazhesko Institute of Cardiology National Academy of Medical Sciences of Ukraine"

Essay

The dissertation is devoted to study of role of the plasma level of B-natriuretic peptide (BNP) and the polymorphism of angiotensin II type 1 receptor gene (AT1R) in beginning and development of essential hypertension EH) in male patients. The presence of C allele of AT1R is a risk factor of development of EH in male inhabitants of Vinnitsa region. The BNP cut point level (50 pg/ml) was counted up for auxiliary diagnosis of left ventricular diastolic dysfunction

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