Іvashchenko O. Anesthesiological supportly of urgent surgery at newborns with apparent hypoxic–ischemic deficiency of the central nervous system.

The dissertation is devoted to the questions of anesthesia and intensive therapy at newborns with an emergency surgical pathology on a background of hypoxic–ischemic affection (HIA) of Central Nervous System (CNS). Work contains a complex of clinical, laboratory, biochemical, physical – chemical and electrophysiological researches under HIA of CNS at newborns with an emergency surgical pathology. It is established that newborn children with a congenital surgical pathology in 95% of supervision are patients with heavy and midheavy degree of HIA of CNS. It was possible to reveal homeostasis characteristic infringements of parameters and on this basis to develop a technique of definition of operational-anesthesiological risk (OAR) degree depending on heaviness of CNS affection. Use of adequate anesthesia and complex pathogenetic proved therapy has allowed to reduce twice stay on AVL (artificial ventilation of lungs) the given contingent of patients and also quantity of chronic bronchial lung and neurologic complications to 30% to reduce lethality up to 29 %.