Kosenko Y. Pathogenetic mechanisms of interaction of bacterial lipopolysaccharides with human blood monocytes and lymphocytes in vitro

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0406U004395

Thesis Registration Form

0406U004395.pdf

Applicant for

Kosenko Yuri Valerievich

Specialization

14.03.04 - Патологічна фізіологія

Date of defense

03-11-2006

Specialized Academic Board

Д 29.600.02

Essay

The thesis is dedicated to problems of analysis of influencing of Gram-negative causative agents of chronic parodontitis lipopolysaccharides on functional activity of monocytes and lymphocytes of human blood. Thus have used bacteriological, immune, biochemical and experimental methods with realisation of the comparative factor analysis of the obtained digital outcomes. It was established dose-dependent and species-specific influence of Gram-negative bacteria lipopolysaccharides on cytokine-productive capacity of monocytes and lymphocytes of human blood, on cytophagous activity and apoptosis of monocytes, apoptosis of T- and B - lymphocytes. The outcomes of research are used in educational process of 2 departments of medical higher schools of Ukraine.

Thesis supervisor

Flegontova Veronica Valentinovna

Official opponents

Сидорчук Ігор Йосипович
Файфура Василь Васильович

Files

автореферат-Косенко.doc

диссертация-Косенко.doc

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