Sopova I. Role of the photoperiod in regulation of peroxidation processes in the basal ganglia of the rat brain under acute hypoxia

The dissertation is devoted to studying of influence of photoperiodic changes on course of peroxidation processes in the basal ganglia of the rat brain under acute hypoxia. It is established, that the changed photoperiod causes the modification of reactions in organism on action of acute stress, in particular to acute hypoxia. At the same time constant light strengthens sensitivity of neurons of basal ganglia to acute hypoxia due to increase as intensity of lipid peroxidation and fibers and constant darkness before acute hypoxia causes increase in a level of the oxidized fibers in the basal ganglia but reduces development lipid peroxidation. Introduction melatonin in a doze of 1 mg per kg of the body mass before modelling acute hypoxia an animals containing in the conditions of the different photoperiod (both usual and changed) mainly promotes approximation norm of parameters of peroxidation processes in the basal ganglia