Glavatska V. Complex hygienic evaluation of regional peculiarities of contamination of environmental objects with lead and its impact on findings of children's health

The object is the influence of technogenic lead on donosologis parameters of children's health. The objective is to give a complex hygienic estimation of lead contents in an environment of ecologically unfavourable region and its influence on donosologis parameters of children's health. And also the objective consist in elaboration, introduction and estimation the efficiency of individual prophylaxis. The methods are hygienic, sociological, biochemical, psychophysiological, microbiological, immunological, statistical. The novelty is specious regularities of distribution, the comparative hygienic estimation of lead contents in various objects of an environment and in children organism of preschool age of the industrial and control regions. It was set the degree of negative influence of lead on the child organism at various levels of its complex action according to biomonitoring, biochemical, immunological and psychophysiological parameters. It was proved, that in despite of conformity of contained leadin objects of an environment of industrial regions to existing standards, its complex and regular entering in children's organism forms significant internal pollution which is caused by ability of this toxic to its accumulation, and also it's caused by intensity of preschool children metabolism. It was set utmost concentration of lead in air and food stuffs, which predetermine excess of admissible values of internal lead pollution of an organism at its complex entering. It was got the findings about the mechanism of hygienic efficiency of the pectinaceous dragee at children's health for decrease the negative risk of lead action. The results consist in realization the comparative hygienic estimation of contained lead in objects of an environment and dynamics of an exposition of the children's population of industrial and control regions. And also was set utmost lead concentration in objects of an environment and biosubstratum, and its biochemical marker of influence, which excess can cause infringement of internal constants and psychophysiological status of preschool age children. It was published the method of individual biopreventive maintenance and its efficiency was proved. It was published the informational letter "Application of a pectinaceous dragee for prophylaxis of children's pathologies, caused by influence of heavy metal". It was introduced in work of the Dnepropetrovsk and Novomoskovsk city sanitary-and-epidemiologic stations, children's clinical hospital №5 of Dnepropetrovsk, and also in educational process of faculties of the general hygiene and ecology of the Zaporozhye state medical university and the Dnepropetrovsk base medical school. The branch is medicine (hygiene).