Romanenko T. Improvement of the system of epidemiological supervision for measles at the elimination stage of this infecion

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U000573

Applicant for

Specialization

  • 14.02.02 - Епідеміологія

06-02-2007

Specialized Academic Board

Д 26.614.02

Essay

Object of the research: epidemic and infectious process of measles infection, anti-measles immunity of the population, epidemiological supervision for measles. Purpose: to develop the ways of improvement of epidemiological supervision for measles and the recommendations of the increasing efficiency of the vaccine prophylaxis measles at the elimination stage. Methods: epidemiological, serological, clinical, statistical. Results: The dissertation is devoted to the study of efficiency of the operating system of the epidemiological supervision for a measles at population and organismic levels and defining the ways of its improvment; the vaccine control of measles and possibility of its elimination in the future are confirmed; authenticity of epidemic unhappiness on measles in the near time among persons from the groups of risk was prognosing, their additional immunization is offered out of the plan; the insufficient protection from a measles is set of new-born in connection with low by the level of immunity of their mothers; interkurrent diseases and type of rearing have a big influence on the state of anti-measles immunity of the babies; primary hospitalization of teenagers and adult 20-29 years with the measles is based, more heavy and protracted clinical flow, more frequent complications are set at uninstiled people; a new chart of epidemiology supervision after a measles is developed. Scientific novelty: first by the systems analysis efficiency of the operating system of epidemiology supervision for measles is appraised on organismic and population levels and recommendations of its improvement are developed; description of quantitative and high-quality displays of epidemic process of measles in the Donetsk region have been given since introduction of specific immunoprophylaxis after a too-doses chart (1987-1999) and at the elimination stage (2000-2005); primariness of the immunological monitoring of efficiency was shown at the elimination stage in the conditions of sporadic morbidity or its absence, expedience of introduction of the united system of epidemiological supervision for a measles and rubella is shown; a new information is got: the degree of protected from the measles of new-born and children of the first year of life depend on the level of specific immunity of their mothers and type of rearing. Degree of introduction: the results of the research, а methodical recommendations the "Epidemiological supervision for measles" were introduced into the work of 6 regional sanitary epidemiological stations, in an educational process of 5 departments of higher medical schools in Ukraine. The sphere of using: medicine (epidemiology).

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