Nikolayeva S. Pregravida preparation and pregnancy management in patients with miscarriage against the background of herpes viral infection

The dissertation is devoted to a problem of miscarriage of herpes viral etiology which is quite urgent in scientific and practical aspect and methods of its prevention and treatment. It is established that carrying out of differentiated pregravida preparations with inclusion of proteflazide and geviran with correction during pregnancy with proteflazide in patients with miscarriage against the background of herpetic infection is pathogenetically proved, promotes correction of the function of the immune system: increase of the general number of T- and B-lymphocytes, increase of the immunoregulation index CD4/CD8, reduction of CIC concentration, reduction of intensity of virus replication and reduction of the level of antigenic loading, influences positively on the course of pregnancy, promotes reduction in recurrence of herpetic infection by 70%, frequencies of threatening miscarriage by 55%, placentary dysfunction by 35%, premature birth by 29,5% and total perinatal losses by 35%.