Shabelnyk K. Synthesis, physico-chemical and biological properties of amides (6-R-4-oxo-4Н-quinazolin-3-yl)alkyl(aryl)carboxylic acids

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U005355

Thesis Registration Form

0407U005355.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

21-12-2007

Specialized Academic Board

Д 35.600.02

Danylo Halytsky Lviv National Medical University

Essay

Object - 4(3Н)quinazolone, 6-nitro-4(3Н)quinazolone and (6-R-4-oxo-4Н-quinazolin-3-yl)alkyl(aryl)carboxylic acids derivatives; methods - synthesis, UV-, IR-, NMR-, mas-, chromato-mass-spectroscopies, pharmacological screening; novelty - the preparative methods of synthesis were developed and series of new (6-R-4-oxo-4Н-quinazolin-3-yl)alkyl(aryl)carboxylic acids amides were obtained, one-pot synthesis of (4-oxy-4Н-quinazolin-3-yl)benzoic acids is elaborated, pharmacological screening of antiradical, antioxidant, hepatoprotective, antiamnestic, neuroprotective and anticancer activity; the outcomes - are introduced into scientific and educational process of pharmaceutical chemistry, organic chemistry departments of National Pharmaceutical University, pharmaceutical, organic and bioorganic chemistry department of L'viv National Medical University, pharmaceutical chemistry and pharmacology department of Ternopol' State Medical University; area - pharmacy.

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Files

aref.doc

Вступ, розділ1-ВСТУП, розділ 1.doc

Додатки-Додатки.doc

Загальні висновки-Загальні висновки.doc

Література-Література.doc

Розділ2-Розділ 2.doc

Розділ3-Розділ 3.doc

Розділ4-Розділ 4.doc

Розділ5-Розділ 5.doc

Таблиці-Таблиця роз 4.1.doc

Таблиці-Таблиця розд 4.doc

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