Koshovyj O. А creation of а new medicine by complex processing of Eucalyptus viminalis leaves

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U000103

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

21-12-2007

Specialized Academic Board

Д 26.613.04

Essay

This dissertation is devoted to the study of biological active substances (BAS) in Eucalyptus viminalis Labill. leaves and to the creation on their basis by complex processing a new herbal drug ”Eucabol”. The qualita-tive composition and quantitative contents of the basic groups BAS in Eucalyptus viminalis Labill. leaves, it’s waste product remaining after manufacture of dense extract Chlorophylliptus and extract ”Eucabol” were investigated. From Eucalyptus viminalis Labill. leaves, it’s waste product and extract ”Eucabol” 2 phenolcarbonic acids, 5 derivatives hydrocinnamic acids, 6 coumarins, 8 flavonoids, 2 organic acids and allantoin were isolated and their structures were determined; 4 sugars and 22 aminoacids were identified. In Eucalyptus viminalis Labill. leaves 65 substances were identified, and in it’s waste product and extract „Eucabol” – 52 substances. The complex method of obtaining the dry extract „Eucabol” from Eucalyptus viminalis Labill. leaves was developed and protected by the patentsof Ukraine № 14493 and № 79383. Projects of the ANDs for medical raw materials „Eucalyptus leaves”, „Dry extract ”Eucabol” and the project of specifications „ Eucalyptus viminalis leaves’ waste product” were developed. It was established, that the extract ”Eucabol” concerns to practically nontoxical substances and has antibacterial, antiinflammatory and anabolic activities.

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