Levashov O. Effects of hypokinesia on bone bioelectrical properties

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U001776

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

08-04-2008

Specialized Academic Board

Д 26.198.01

Bogomoletz Institute of Physiology National of science of Ukraine

Essay

The dissertation is devoted to studying of the bone bioelectric properties at the low functional loading. It was set that hard limitation of mobility during for certain diminished of the stress generated potential amplitude, the value of impedance, active and reactive resistances and considerable increased of the bone electrical capacity. The oxygen tension of the low loaded muscles and bone oxygen consumption diminished too. The intermittent normobaric hypoxia prevented of the oxygen metabolism disturbances and activated the anabolic processes in bone tissue. The bone passive electrical properties were improved too. The maximal osteoprotection effect was got in experiments when intermittent normobaric hypoxia was used while of preadaptation period and for all period of hypokinesia. The results of this study may be used for development of new noninvasive diagnostic and correction methods of the bone system pathology.

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