Borisov M. Non-atypical endometrium hyperplasia treatment in women with metabolic syndrome in premenopause

The thesis is devoted to the actual problem of Gynecology - non-atypical endometrium hyperplasia treatment in women with metabolic syndrome in premenopause. Endometrium hyperplasia on the background of the metabolic syndrome in women in premenopause should be considered as a complex endometrium proliferation disturbances, which appear as the result of tissue susceptibility decreasing to insulin on the background of disorders in carbohydrate, lipid metabolisms, hormonal background, abdominal type adipose tissue distribution with following the receptor mechanism changes, increasing of endometrium proliferation activity, and is followed by menstrual cycle disturbances.. In connection with abovementioned the scheme treatment was worked out, where the traditional therapy was done on the background insulin resistance correction. On the background of the treatment done the frequency of endometrium hyperplasia relapses was decreased by 1,9 times, menstrual cycle disturbances were decreased by three times, thefrequency of normal menstrual cycle restoration was increased up two times, the frequency of amenorei increased by 1,4 times.