Omel'chenko Z. Phytochemical study of Setaria italica and a creation of medicine on its base

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U003121

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

20-06-2008

Specialized Academic Board

Д 26.613.04

Essay

The thesis is devoted to phytochemical studies of Setaria italica's grass and fruits (Dniprovska species) and creation some drugs on its basis. Qualitative composition and quantitative content of different groups of biologically active substances in raw material was studied. It was the first time when 56 sub-stances were identified in Setaria italica's grass and fruits: 18 phenolic sub-stances, 2 anhydrosugars, 24 fatty acids, 12 sterols were isolated and their structure was determined. 16 amynoacids, 27 macro- and microelements were also identified there and their quantitative content was determined. The method of obtaining of Setaria italica's grass fluid extract was developed. It was determined this extract almost hasn't got any toxicity and can have anti-inflammatory and diuretic activity. The drafts of Analytical Normative documentation were developed on plant raw material "Setaria italica's grass", "Setaria italica's fruits", "Fluid extract from Setaria italica's grass".

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