Senchenko N. The role of parotid saliva metabolic, immune factors and bacterial persistence in pathogenesis of caries in 5-15 years old children

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U003937

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

05-09-2008

Specialized Academic Board

Д29.600.02

Essay

The thesis clears the role of parotid saliva metabolic, immune factors and bacterial persistence in pathogenesis of caries in 5-15 years old children. The intensity of parotid salivation, oxidative and antioxidant activity of parotid saliva, its influence on coagulation and fibrinolysis are studied in healthy and ill with caries 5-15 years old children. The rate of cellular and humoral immune factors is established for the first time in the parotid saliva of 5-15 years old children. The specific structure of bacteria isolated from caries cavities and bacterial antilysozyme and antiimmunoglobulin activity are studied. The laboratory method for the study of plasminogen activator rate in saliva is worked up, tested and patented.

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