Gontsov Y. Immune and metabolic homeostasis, its disorders and methods of correction at chronic prostatitis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U004338

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

03-10-2008

Specialized Academic Board

Д29.600.02

Essay

The thesis shows the results of immune and metabolic homeostasis study in patients with chronic prostatitis at acute phase and at remission, and proposes pathogenetically based method of treatment with Amisonum and cycloferone usage. The significance of decreased secretion of interleukins-1, -6, tumor necrosis factor by monocytes in immunodeficiency formation in patients with chronic prostatitis is shown. The role of metabolic disorders in the pathogenesis of chronic prostatitis is established: activation of lipid peroxidation, insufficiency of antioxidant defense system, disbalance in eicosanoid system. The complex influence of Amisonum and cycloferone on clinical, immune and metabolic parameters of patients with chronic prostatitis is established for the first time.

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