Polivoda M. Clinical and experimental substantiation of immunotropic effect of galvanic currents in rehabilitation of patients with lower limbs varicosity upon phlebectomy

Object of research: patients with lower limbs varicosity upon phlebectomy.Goal: Experimental and clinical substantiation of immunotropic effects of galvanic currents in the period of postoperative rehabilitation of cases of varicose disease of lower extremities veins, given pathogenetic mechanisms of functioning of the epithelium- associated lymphoid tissue.Methods: biochemical, laboratory, immunological, morphological and statistic.Theoretical and practical results: System of assessment of immunotropic action of galvanic current related to indices of the course of tissue renovation and repair processes in cases of varicose disease of lower extremities veins after venectomy has been formed. Pathogenetically substantiated has been the use of galvanisation courses for purposes of stimulation of the skin epithelium-associated lymphoid tissue. The galvanisation method according to Vermel (N=10) has be suggested as a component of rehabilitation measures after venectomy in cases of varicose disease of lower extremities veins as the method which accelerates postoperative cicatrisation and trophic ulcer epithelisation.Innovative effect: Laws of immunotropic action of galvanic currents, given the Th1/Th2-determined forms of immune reaction have been analysed for the first time in experimental conditions and in the conditions of rehabilitation of cases of varicose disease of lower extremities veins after venectomy. The response of the epithelium-associated lymphoid tissue to the directional action of galvanic currents has been studied for the first time in connection with the dynamics of regeneration processes which manifest themselves in the form of trophic ulcer epithelisation and acceleration of postoperative cicatrisation.Adoption stage: articles, theses, incorporation in higher medical educational establishments’ curriculum.Sphere and branch of application: medicine.