Sukhurova L. Prevention and treatment of gestational complications in pregnant women with irritable bowel syndrome

The thesis is devoted to the solving of the one of the actual problem in obstetrics - decreasing of frequency of pregnancy and labor complications in women with irritable syndrome (IBS). Peculiarities of the gestational process and labor, microbiologic profile of the bowel and vagina, markers of endogenous intoxication, immune state, some biochemical indexes of the blood, fetus state and placenta function were studied in dependent on clinical variant of IBS (with predomination of constipation and with predomination of the pain and meteorism). On the basis of the investigations of the different homeostasis links were done the complex of the medical and preventive measures for pregnancy with IBS, the adoption of which permitted to decrease the frequency of the threat of pregnancy interruption in 3,0, placental deficiency - 1,8, intrauterine growth retardation - 2,2, hydramnion - 2,8, complicated labors - 2,8, untimely discharge of amniotic fluid - 2,7, neonatal asphyxia - 2,3.