Burlaka N. Mechanisms of renal functional reserve in the norm and at toxic nephropathy

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U000584

Thesis Registration Form

0409U000584.pdf

Applicant for

Specialization

  • 14.03.04 - Патологічна фізіологія

23-01-2009

Specialized Academic Board

Д29.600.02

Essay

The peculiarities of renal functional answer were investigated by load with sodium and potassium salts in rats that had the diet with decreased and increased sodium content, and also by load with meat for practically healthy people with registration of renal functional reserve. It was shown that healthy subjects after protein load had changed values of diuresis, excretion of creatine, potassium, ammonia, titrated acids, nitrates, nitrites and their concentrations. Thus the proposed loading causes the increase of creatine excretion that is the consequence of renal reserve activation. The chronic blockade of nitric oxide synthesis in rats disturbs the functional state of kidneys and blockade of renal functional reserve. The proposed methods are recommended for the use in physiology and clinical researches of renal function.

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Files

Dissertation-Burlaka.doc

aref-Burlaka.doc

aref-Burlaka.doc

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