Balia A. Amidophenacylating reagents in the syntheses of the potential bioregulators of 1,3-azole series

Amidophenacylating reagents. Research of transformations of amidophenacylating reagents which result to new types of bisfunctionalized 1,3-аzoles. Chemical synthesis, IR-and PMR-spectroscopy, mass-spectrometry, X-ray research. It was proved that the amidophenacylating reagents continuous reaction with ammonium dithiocarbamate produces derivatives 5-amino-2-mercapto-1,3-thiazole which successfully were transformed into 2-acylaminothiazolo[2,3-b]thiazolium salts. It was found that the products of condensation of oxazoles with methyl chloroacetate are valid for the recyclization. It was solved that the products of condensation of amidophenacylating reagents with mono- and disubstituted thioureas and also thiosemicarbazones under heating in hydrochloric acid recyclizate and produce biophore di- and trisubstituted 2-thiohydantoins. Comparing known structures of the bioregulators of azole series and different derivatives of oxazole, thiazole, imidazole and imidazo[2,1-b]thiazole obtained on the basis of amidophenacylating reagents allows to foresee their high and broad biophore. Nowadays we managed to confirm the derivatives of thiazole influence the growth of wheat and corn. Sphere of use - bioorganic and organic chemistry.