Malinovsky Y. Pharmacognostic and chemico-toxicological study of hemlock spotted

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U001008

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

20-02-2009

Specialized Academic Board

Д64.605.01

Essay

The dissertation is devoted to complex pharmacognostic and chemico-toxicological study of hemlock spotted. In the herb of hemlock was established the presence of polysaccharides, first amino acid, fat acids, micro- and macroelements. 17 matters of phenol nature were identified, from them 13 for this kind of herb at first time. The modern method of qualitative and quantitative definition of coniine at the raw material of hemlock and biological material of animal origin was developed. The plan for research of biological material, suitable for a chemico-toxicological analysis of coniine was offered. The method of receiving of complex of polysaccharides from hemlock was developed and confirmed by the patent of Ukraine on an useful model. The basic anatomo-diagnostic signs of fruits and herb of hemlock were first established by comparison to near kinds -Chaerophyllum Prescottii and Petroselinum crispum. Methodical recommendations were published on the basis of results of researches, and the project of the analytical normative documentation was developed.

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