Fedchenkova J. Pharmacognostic study of some representatives of Acer L. genus and prospects of using them in medicine

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U002140

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

17-04-2009

Specialized Academic Board

Д 64.605.01

National University of Pharmacy

Essay

The thesis is devoted to the systemic pharmacognostic study of the most common representatives of Acer genus: Acer negundo, Acer platanoides and Acer campestre. 21 substances have been isolated from leaves and bark of Acer and their structures have been determined. 7 compounds have been isolated for the first time from this plant. The Lipophilic fraction has been taken and studied from bark, leaves and seeds of Acer. The qualitative composition and qualitative content of macro- and microelements and fatty acids have been dextermined. The quantitative content of organic acids, ascorbic acid and different groups of phenolic compounds have been determined. The Technology of obtaining dense extracts from leaves of Acer negundo have been developed and The Technology of obtaining dense extracts from leaves of Acer negundo have been approved in cinditions of Zdorovya, Ltd. The standardization of the raw material and substances has been carried out, their projects of AND have been developed. The complex of research of the biological activity has proven the availabilityof developing medicines with the antimicrobial, cytotoxic and spermicidal activity on their basis.

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