Karpiuk U. Phytochemical study of Glycine hispida’s commercial species and creation of drug substances on its basis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U002548

Thesis Registration Form

0409U002548.pdf

Applicant for

Specialization

  • 15.00.02 - Фармацевтична хімія та фармакогнозія

28-05-2009

Specialized Academic Board

Д 26.613.04

Essay

The dissertation is devoted to the comparative pharmacognostical study the biological active substances (BAS) of Glycine hispida grass in the stage of flowering of Skelya, Feya and Podolskaya species. The qualitative composition and quantitative content of groups BAS in studied raw material were determinated. By the methods of column and preparation chromatography 28 substances were obtained in the individual state. Gallic acid acid and ?-sitosterol were isolated from the grass of soy for the first time. The methods of receipt of thick extract were determined, its acute toxicity, аnabolic, antioxidant, hepatoprotective, antioxidant and hypoglycemic activity to the intestine were studied. The following draft sets of AND for the medical raw materials: “Glycine hispida grass”, “Glycine hispida grass thick extract” were developed.

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Files

автореферат карпюк.doc

диссертация карпюк.doc

диссертация карпюк.doc

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