Kucherenko O. Toxicological and hygienic assessment of modern technologies chemical rice crop protection.

Object of study. Laws of behavior in the environment of the active ingredients in pesticides which are contained in the chemical protection of the rice crop, and the risk of it’s complex influence on the workers and the population of Ukraine. Purpose.To make an toxicological and hygienic assessment, and scientifically base safety regulations for the use of modern pesticide in chemical rice protection, to minimize the potential risk of unwanted effects on the workers and the population. Methods. Laboratory and full-scale hygienic experiments, under conducting of which there have been used toxicological, sanitary-chemical, chemical and analytical (including chromatographic), sanitary-microbiological, biochemical, clinicodiagnostic methods, analysis of variance, correlation analysis, regression procedure, and mathematical modeling. Theoretical and practical results.Developed and ratified a complex of hygienic norms and regulations, their application with pesticides Hurricane Forte 500 SL, Reglon Super 150 SL, Karate of Zeon 050 CS, Tilt 250 ES, Maksim 025 FS and Nomini 400 in the system of chemical protection of rice crops. Scientifally based acceptable daily intake of bispiribak-natrii for humans, it’s hygienic norms in objects of the surrounding environment, the maximum acceptable dose of bispiribak-natrii, lambda-cyhalothrine, propiconazole, diquat dibromid, fludioksonil per grain of rice; the duration of time in which workers may cultivate the field after the use of pesticides and the term of expectation to collection of harvest. Novelty. For the first time in Ukraine, there are laws for migration of pesticides, active ingredients of bispiribak-natrii, lambda-cyhalothrine, propiconazole, diquat dibromid, fludioksonil into plantlife, soil, and water. Research of the working conditions under the use of pesticides and the forecast of potential risk for workers. Developed the regulations of migration of bispiribak-natrii in the system of soil-groundwater and the environment, based the hygienic norms of the environment (soil, air, plants and water) and rice grains. There are regularities of effects of bispiribak-natrii on the processes of self-restoration of reservoirs and the organoleptic characteristics of water. Scientifically based the most optimal method of preparing samples of soil water air, and rice grains, and the conditions of quality identification and quantification of bispiribak-natrii using the сhromatographic method. Scope of use. Medicine, Agriculture.