Lutsenko Y. Forecasting and preventive measure of sanguifluous acute erosions, ulcers gastric and duodenal for patients with a acute pancreatitis

The purpose - to improve the results of treatment of patients with acute pancreatitis by means of development of forecast criteria and prevention of development of bleeding acute erosions, gastric and duodenal ulcers; The object - bleeding acute erosions, gastric and duodenal ulcers in patients with acute pancreatitis; Research methods - clinical, biochemical, immunological, endoscopical, statistical and mathematical; Scientific novelty - It has been established for the first time that the level of pancreatic amylase in blood and sensitization of organism to tissues of parietal, visceral peritoneum and stomach are the most significant indexes to forecast bleeding acute erosions, gastric and duodenal ulcers in patients with acute pancreatitis. These indexes are included into the mathematical forecasting model with p<0.0001 confidence; Results - The developed algorithm of forecast and prevention of bleeding acute erosions, gastric and duodenal ulcers in patients with acute pancreatitis gives the opportunity to conduct the rational correction of complex therapy in time. It has been established that the forecast criteria developed by us help to carry out preventive measures directed on prevention of development of bleeding acute erosions, gastric and duodenal ulcers in patients with acute pancreatitis. The developed chart of prevention of acute ulcers and erosions of stomach and duodenum formation allowed to reduce development of bleeding acute erosions, gastric and duodenal ulcers from 22.7 % in the test group to 10.5 % in the basic group of patients; it has been introduced into medical practice and studying process; sphere - medicine.